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Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily. It is vital for brain development. Mutations, rearrangements, and amplifications in the ALK gene have been found in tumors, including anaplastic large cell lymphoma, neurblastoma, and non-small cell lung cancer. Chromosomal rearrangement is the most common genetic alteration.
Learn more about our kinase proteins >
Related Links:
LanthaScreen™ Kinase Activity Assay
LanthaScreen™ Eu Kinase Binding Assay
Learn more about our kinase proteins >
Related Links:
LanthaScreen™ Kinase Activity Assay
LanthaScreen™ Eu Kinase Binding Assay
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_004295
Gene ID (Entrez)
238
Molecular Weight
89.9 kDa
Quantity
100μg
Gene Alias
CD246, NBLST3
KinaseFamily
ALK Kinase Family
Recombinant
Yes
Protein Tag
GST Tag
Kinase Group
Receptor Tyrosine Kinase
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Active, Cytoplasmic
Form
Liquid
Protein Subtype
Receptor Tyrosine Kinases
Validated Application
Kinase Assay
Species
Human
Research Category
Signal Transduction
Contents & Storage
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.