MET (cMET) is a receptor-like tyrosine kinase whose disregulation has been linked to many types of human malignancies. The M1250T mutant of MET is both activating and displays altered substrate specificity.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_000236.2, M1250T
Molecular Weight
53.7 kDa
Quantity
100 µg
Gene Alias
MET M1250T
KinaseFamily
MET (HGFR) Kinase Family
Recombinant
Yes
Protein Tag
His Tag
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Form
Cytoplasmic
Form
Frozen
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Development
Contents & Storage
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.