FRAP1 (mTOR) is a serine⁄threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR⁄PI3-kinase⁄AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics.
For Research Use Only. Not for use in diagnostic procedures.
PIKK Kinase Family
Ser⁄Thr Kinases: Atypical
LanthaScreen™ Antibody, Zin-LYTE™
FK506 binding protein 12-rapamycin associated protein 1
Kinases & Inhibitors
Signal Transduction, Drug Development, Oncology
Contents & Storage
Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.1% Polysorbate 20, 2 mM DTT, 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.