For order quantities > 1, multiple lots may be used to fulfill the order. If you require a single lot, please email discoverysciences@lifetech.com.

During checkout, this product will be reported as "Out of Stock" with an estimated availability date. Often, the actual availability date will be earlier. Send inquiries regarding actual availability date to discoverysciences@lifetech.com.

88 more kinases now available to order! See the complete list.
Thermo Scientific™

SPHK1 Recombinant Human Protein

Catalog number:  PR8902A

Related applications:

Protein Assays and Analysis

Back to top

Description

SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signalling molecule sphingosine-1-phosphate (S1P). S1P signals through G-protein coupled receptors and controls diverse cellular processes. Inhibitors of SPHKs are viewed as potential therapuetics for the treatment of cancer.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_068807.2
Kinase Group: Lipid Kinases
Shipping Condition: Dry Ice
Expression System: Baculovirus
Form: Frozen
Protein Form: Full Length
Research Category: Drug Development
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 71.4 kDa
Gene Alias: SPHK1
KinaseFamily: SPHK and DGCK Kinase Family
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Triton X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.