EIF2AK2 (PKR) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses. EIF2AK2 plays a key role in antiviral defense mediated through its direct activation by double-stranded RNA produced by viral infection.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_002750.1
Molecular Weight
62.2 kDa
Quantity
100 µg
Gene Alias
EIF2AK2 (PKR)
KinaseFamily
PEK Kinase Family
Protein Length
aa 252-551
Host Species
Human
Recombinant
Yes
Protein Tag
GST Tag
Kinase Group
Ser⁄Thr Kinases: Other
Shipping Condition
Dry Ice
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Catalytic
Form
Liquid
Validated Application
Kinase Assay
Species
Human
Research Category
Signal Transduction
Contents & Storage
Storage Buffer: 50 mM Tris, pH 7.5, 50% glycerol, 0.5 mM EDTA, 0.02% Triton X-100, 150 mM NaCl, 2 mM DTT Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.