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EIF2AK2 (PKR) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses. EIF2AK2 plays a key role in antiviral defense mediated through its direct activation by double-stranded RNA produced by viral infection.
For Research Use Only. Not for use in diagnostic procedures.
Ser⁄Thr Kinases: Other
PEK Kinase Family
Contents & Storage
Storage Buffer: 50 mM Tris, pH 7.5, 50% glycerol, 0.5 mM EDTA, 0.02% Triton X-100, 150 mM NaCl, 2 mM DTT Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.