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      MAP3K14 (NIK) Recombinant Human Protein

      Catalog number: PR8920A

       Related applications: Protein Assays and Analysis

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      Description

      MAP3K14 (NIK) is structurally related to MAP3Ks. MAP3K14 phosphorylates and activates CHUK (IKKalpha) and IKBKB (IKK beta), which in turn phosphorylate IkB-alpha, releasing NF-KappaB leading to up-regulation of inflammatory response genes.
      For Research Use Only. Not for use in diagnostic procedures.

      Specifications

      Research Category: Drug Development
      Accession Number: NP_003945.2
      Form: Frozen
      Gene Aliases: MAP3K14 (NIK)
      Kinase Group: Ser⁄Thr Kinases: STE Group
      Molecular Weight: 96.9 kDa
      Product Size: 100 µg
      Species: Human
      Validated Application: Kinase Assay
      Protein Tag or Fusion: GST Tag
      Expression: Baculovirus
      Kinase Family: STE Unique Kinase Family
      Protein Form: Catalytic
      Shipping Condition: Dry Ice

      Contents & storage

      Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.02% Trition X-100, 0.5 mM EDTA, 2 mM DTT, 50% Glycerol
      Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

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