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EIF2AK3 (PERK) Recombinant Human Protein

Catalog number:  PR8985A

Related applications:

Protein Assays and Analysis

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Description

EIF2AK3 (PERK) is one of 4 kinases that specifically phosphorylate Ser51 of translation initiation factor eIF2-alpha in response to various environmental stresses, leading to a decrease in protein sythesis. In the case of EIF2AK3, signaling is initiated by misfolded proteins in the ER.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_004827.3
Kinase Group: Ser⁄Thr Kinases: Other
Shipping Condition: Dry Ice
Expression System: Baculovirus
Form: Frozen
Protein Form: Catalytic
Research Category: Drug Development
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 93.6 kDa
Quantity: 100μg
Gene Alias: EIF2AK3 (PERK)
KinaseFamily: PEK Kinase Family
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.