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PRKCI (PKC iota) Recombinant Human Protein

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Description

The PKC family of serine⁄threonine kinases, including PRKCI (PKC iota), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Protein Family: Kinases & Inhibitors
Research Category: Signal Transduction
Accession Number: NP_002731
Gene Aliases: PRKCI (PKC iota)
Gene ID: 5584
Kinase Group: Ser⁄Thr Kinases: AGC Group
Molecular Weight: 71.5 kDa
Product Size: 5 µg
Protein Subtype: Serine⁄Threonine Kinases
Species: Human
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Omnia® Bulk Substrate, Z'-LYTE™
Target Gene: protein kinase C, iota
Validated Application: Kinase Assay
Protein Tag or Fusion: His Tag
Expression: Baculovirus
Kinase Family: PKC Kinase Family
Protein Form: Full Length, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 20mM HEPES, pH 7.5, 150mM NaCl, 0.5mM EGTA, 0.5mM EDTA, 0.05% NP-40, 5mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

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