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ErbB2 (HER2)

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Description

ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_004439
Expression: Baculovirus
Gene Aliases: ErbB2 (HER2), NEU
Gene ID: 2064
Kinase Family: EGF Receptor (ErbB) Kinase Family
Kinase Group: Tyrosine Kinases
Molecular Weight: 68.6 kDa
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Form: Cytoplasmic,Recombinant
Protein Length or Portion (a.a.): aa 676-1255
Protein Subtype: Receptor Tyrosine Kinases
Protein Tag or Fusion: His Tag
Research Category: Oncology,Signal Transduction
Shipping Condition: Dry Ice
Species: Human
System Compatibility: LanthaScreen® Antibody,LanthaScreen® Substrate,Z'-LYTE™
Target Gene: V-erb-b2 erythroblastic leukemia viral oncogene homolog 2
Validated Application: Kinase Assay

Contents & storage

Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.01% CHAPS, 2mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.