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BRAF Recombinant Human Protein

Catalog number:  PV3848

Related applications:

Pharma & Biopharma

| Protein Assays and Analysis

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Description

BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is activated by somatic point mutation in human cancer, and is thought to play a role in the postsynaptic responses of hippocampal neuron.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_004324.2
Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group: Ser⁄Thr Kinases: TKL Group
Protein Form: Full Length, Recombinant
Research Category: Oncology, Signal Transduction
Shipping Condition: Dry Ice
Species: Human
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™, Omnia® Bulk Substrate
Target Entry: BRAF
Target Gene: v-raf murine sarcoma viral oncogene homolog B1
Gene ID (Entrez): 2353, 673
Molecular Weight: 113.6 kDa
Protein Subtype: Serine⁄Threonine Kinases
Gene Alias: BRAF, BRAF1
Validated Application: Kinase Assay
Protein Family: Kinases & Inhibitors
Expression System: Baculovirus
KinaseFamily: RAF Kinase Family
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.