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BRAF Recombinant Human Protein

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Description

BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It is activated by somatic point mutation in human cancer, and is thought to play a role in the postsynaptic responses of hippocampal neuron.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Protein Family: Kinases & Inhibitors
Research Category: Oncology, Signal Transduction
Accession Number: NP_004324.2
Gene Aliases: BRAF, BRAF1
Gene ID: 2353, 673
Kinase Group: Ser⁄Thr Kinases: TKL Group
Molecular Weight: 113.6 kDa
Product Size: 10 µg
Protein Subtype: Serine⁄Threonine Kinases
Species: Human
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Omnia® Bulk Substrate, Z'-LYTE™
Target Gene: v-raf murine sarcoma viral oncogene homolog B1
Validated Application: Kinase Assay
Protein Tag or Fusion: GST Tag
Expression: Baculovirus
Kinase Family: RAF Kinase Family
Protein Form: Full Length, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 2mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

Documents

Manuals & protocols