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ABL1 [Y253F] Recombinant Human Protein

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The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. The Y253F mutant is a Gleevec resistant form of ABL1.
For Research Use Only. Not for use in diagnostic procedures.


Gene ID: 25, 9586
Species: Human
Target Gene: c-abl oncogene 1, receptor tyrosine kinase
Gene Aliases: ABL1 Y253F, ABL, c-ABL
Product Size: 10 µg
Protein Form: Full Length, Cytoplasmic, Recombinant
Protein Family: Kinases & Inhibitors
Protein Subtype: Cytoplasmic Tyrosine Kinases
Accession Number: NP_005148.2, Y253F
Molecular Weight: 125.4 kDa
Research Category: Signal Transduction, Oncology
System Compatibility: LanthaScreen® Substrate, Omnia® Bulk Substrate, LanthaScreen® Antibody, Z'-LYTE™
Validated Application: Kinase Assay
Protein Length or Portion (a.a.): Full Length (Y253F)
Protein Tag or Fusion: His Tag
Expression: Baculovirus
Kinase Family: ABL Kinase Family
Kinase Group: Tyrosine Kinases
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% NP-40, 2 mM DTT and 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.


Manuals & protocols