ALK Recombinant Human Protein

Catalog number:  PV3867

Related applications:

Protein Assays and Analysis

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Description

Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily. It is vital for brain development. Mutations, rearrangements, and amplifications in the ALK gene have been found in tumors, including anaplastic large cell lymphoma, neurblastoma, and non-small cell lung cancer. Chromosomal rearrangement is the most common genetic alteration.

Learn more about our kinase proteins >

Related Links:

LanthaScreen® Kinase Activity Assay
LanthaScreen® Eu Kinase Binding Assay
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_004295, NP_004295.2, J1461V
Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic
Kinase Group: Tyrosine Kinases
Shipping Condition: Dry Ice
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Z'-LYTE™, Omnia® Bulk Substrate
Target Entry: ALK
Target Gene: anaplastic lymphoma receptor tyrosine kinase
Expression System: Baculovirus
Protein Form: Recombinant, Active, Cytoplasmic
Research Category: Drug Development
Species: Human
Validated Application: Kinase Assay
Gene ID (Entrez): 114294, 238, 238
Molecular Weight: 89.9 kDa, 90 kDa
Quantity: 10μg
Gene Alias: CD246, NBLST3
KinaseFamily: ALK Kinase Family
Protein Length: aa 1058-1620
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.