For order quantities > 1, multiple lots may be used to fulfill the order. If you require a single lot, please email discoverysciences@lifetech.com to ensure your needs are accommodated

88 more kinases now available to order! See the complete list.
Thermo Scientific™

MET [M1250T] Recombinant Human Protein

Catalog number:  PV3968

Related applications:

Protein Assays and Analysis

Back to top

Description

MET (cMET) is a receptor-like tyrosine kinase whose disregulation has been linked to many types of human malignancies. The M1250T mutant of MET is both activating and displays altered substrate specificity.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_000236.2, M1250T
Assay Entry: Biochemical terbium phospho-specific activity, Biochemical binding/kinetic
Kinase Group: Tyrosine Kinases
Mass: 10 µg
Shipping Condition: Dry Ice
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Zin-LYTE™, Omnia® Bulk Substrate
Tag Position: N-Terminal
Target Entry: MET M1250T
Target Gene: met proto-oncogene
Expression System: Baculovirus
Protein Family: Kinases & Inhibitors
Protein Form: Recombinant, Cytoplasmic
Protein Subtype: Receptor Tyrosine Kinases
Research Category: Signal Transduction
Species: Human
Validated Application: Kinase Assay
Gene ID (Entrez): 4233, 4790
Molecular Weight: 53.7 kDa
Gene Alias: MET M1250T
KinaseFamily: MET (HGFR) Kinase Family
Protein Length: aa 956-1390; M1250T
Protein Tag: His Tag

Contents & storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.