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MET [M1250T] Recombinant Human Protein

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Description

MET (cMET) is a receptor-like tyrosine kinase whose disregulation has been linked to many types of human malignancies. The M1250T mutant of MET is both activating and displays altered substrate specificity.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_000236.2, M1250T
Expression: Baculovirus
Gene Aliases: MET M1250T
Gene ID: 4233, 4790
Kinase Family: MET (HGFR) Kinase Family
Kinase Group: Tyrosine Kinases
Mass: 10 µg
Molecular Weight: 53.7 kDa
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Form: Cytoplasmic,Recombinant
Protein Length or Portion (a.a.): aa 956-1390; M1250T
Protein Subtype: Receptor Tyrosine Kinases
Protein Tag or Fusion: His Tag
Research Category: Signal Transduction
Shipping Condition: Dry Ice
Species: Human
System Compatibility: LanthaScreen® Antibody,LanthaScreen® Substrate,Omnia® Bulk Substrate,Z'-LYTE™
Tag Position: N-Terminal
Target Gene: met proto-oncogene
Validated Application: Kinase Assay

Contents & storage

Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.