MAP4K2 (GCK) is a serine⁄ threonine protein kinase that activates the JNK pathway. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of the germinal center, where it may participate in B-cell differentiation. The kinase may also play a role in the regulation of vesicle targeting or fusion.
For Research Use Only. Not for use in diagnostic procedures.