ACVR1B is a serine⁄threonine kinase involved in signal transduction and cellular communication. Several truncated ACVR1B isoforms have been reported to be exclusively expressed in human pituitary tumors. Mutations of ACVR1B have been observed in pancreatic adenocarcinomas.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
For Use With (Application)
Kinase Assay
Molecular Weight
68.2 kDa
Product Type
Recombinant Human Protein
Quantity
1 mg
Format
Frozen
Expression System
Baculovirus
Protein Form
Catalytic
Protein Tag
GST Tag
Shipping Condition
Dry Ice
Research Category
Drug Development
Species
Human
Validated Kinases
Ser/Thr Kinases: TKL Group
Contents & Storage
Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton™ X-100, 2 mM DTT, and 50% Glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.