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Thermo Scientific™

RET [V804L] Recombinant Human Protein

Catalog number:  PV4397

Related applications:

Protein Assays and Analysis

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Description

The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development, and can undergo oncogenic activation by cytogenetic rearrangement. The V804L mutant has been observed in association with cancer.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number: NP_066124, V804L
Assay Entry: Biochemical phospho-specific activity (no antibody), Biochemical terbium phospho-specific activity, Biochemical europium phospho-specific activity, Biochemical binding/kinetic
Kinase Group: Tyrosine Kinases
Mass: 10 µg
Shipping Condition: Dry Ice
System Compatibility: LanthaScreen® Antibody, LanthaScreen® Substrate, Zin-LYTE™, Omnia® Bulk Substrate
Tag Position: N-Terminal
Target Entry: RET V804L
Target Gene: ret proto-oncogene
Expression System: Baculovirus
Protein Family: Kinases & Inhibitors
Protein Form: Recombinant, Cytoplasmic
Protein Subtype: Receptor Tyrosine Kinases
Research Category: Oncology, Signal Transduction
Species: Human
Validated Application: Kinase Assay
Molecular Weight: 79.0 kDa
Gene Alias: RET V804L
KinaseFamily: RET Kinase Family
Protein Length: aa 658-1114; V804L
Protein Tag: GST Tag

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton X-100, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.