MELK is a serine⁄threonione kinase which is related to the AMPK family that has been linked to the cell cycle. MELK has also been shown to be overexpressed in cancer and has been identified has a potential target for cancer therapeutics.
For Research Use Only. Not for use in diagnostic procedures.
Gene ID (Entrez)
95% by SDS-PAGE
CAMLK Kinase Family, CAMKL Kinase Family
Biochemical binding/kinetic, Biochemical phospho-specific activity (no antibody)
Ser⁄Thr Kinases: CAMK Group
maternal embryonic leucine zipper kinase
Kinases & Inhibitors
Drug Discovery: Oncology, Signal Transduction
Contents & Storage
Storage Buffer: 50 mM Tris, pH 7.5, 50% glycerol, 0.5 mM EDTA, 0.02% Triton X-100, 150 mM NaCl, 2 mM DTT Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.