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EGFR (ErbB1) [T790M] [L858R] Recombinant Human Protein

Catalog number: PV4879

EGFR (ErbB1) [T790M] [L858R] Recombinant Human Protein

Catalog number: PV4879
Catalog Number
PV4879
Unit Size
10 µg
Price (USD)
451.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
1,546.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
6,570.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV487910 µg
451.00
Your Price:
***
PR8911A100 µg
1,546.00
Your Price:
***
PV48801 mg
6,570.00
Your Price:
***
Product Overview
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Additional Information
Recommendations
The epidermal growth factor receptor is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. The double T790M L858R mutant of EGFR displays resistance to Erlotinib (Tarceva) and sensitivity to HKI-272 and rapamycin combination therapy.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NP_005219.2; T790M L858R
Assay Entry
Biochemical binding/kinetic
Kinase Group
Tyrosine Kinases
Shipping Condition
Dry Ice
System Compatibility
Z'-LYTE™
Target Entry
EGFR T790M L858R
Target Gene
Epidermal growth factor receptor
Expression System
Baculovirus
Form
Liquid
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Cytoplasmic
Protein Subtype
Receptor Tyrosine Kinases
Research Category
Oncology, Signal Transduction
Species
Human
Validated Application
Kinase Assay
Gene ID (Entrez)
1956
Molecular Weight
90.6 kDa
Quantity
10 µg
Gene Alias
EGFR (ErbB1) T790M L858R
KinaseFamily
EGF Receptor (ErbB) Kinase Family
Protein Length
aa 668-1210; T790M, L858R
Recombinant
Yes
Protein Tag
GST Tag

Contents & Storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Polysorbate 20, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

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