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LRRK2 [G2019S] Recombinant Human Protein

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LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in this gene have been associated with Parkinson's disease. The G2019S mutation of LRRK2 is associated with an increase in catalytic activity.

Related Links:
LRRK2 tools for advancing Parkinson's disease research
Kinase protein portfolio
LanthaScreen® Eu Kinase Binding Assay
LanthaScreen® Activity Assay
For Research Use Only. Not for use in diagnostic procedures.


Gene ID: 120892
Species: Human
Target Gene: Leucine-rich repeat kinase 2
Gene Aliases: LRRK2 G2019S
Kinase Group: Ser⁄Thr Kinases: TKL Group
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Subtype: Serine⁄Threonine Kinases
Accession Number: NP_940980.2, G2019S
Molecular Weight: 204.9 kDa
Research Category: Neurobiology, Signal Transduction
System Compatibility: LanthaScreen® Substrate, LanthaScreen® Antibody, Adapta™
Validated Application: Kinase Assay
Protein Length or Portion (a.a.): aa 970-2527; G2019S
Protein Tag or Fusion: GST Tag
Expression: Baculovirus
Kinase Family: LRRK Kinase Family
Protein Form: Catalytic, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris pH 7.5, 150 mM NaCl, 0.5 mM EDTA, 0.02% Polysorbate 20, 2 mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.


Manuals & protocols

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