Thermo Scientific™

AMPK (A2/B2/G1) Recombinant Human Protein

Catalog number: PV6247
Thermo Scientific™

AMPK (A2/B2/G1) Recombinant Human Protein

Catalog number: PV6247
Catalog Number
PV6247
Unit Size
10 µg
Price (USD)
Price: 499.00
Your Price:
Availability
-
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
Price: 1,708.00
Your Price:
Availability
-
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
Price: 7,660.00
Your Price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV624710 µg
Price: 499.00
Your Price:
-
PV6248100 µg
Price: 1,708.00
Your Price:
-
PV62491 mg
Price: 7,660.00
Your Price:
-
Product Overview
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Additional Information
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AMP-activated protein kinase (AMPK) exhibits a key role as a master regulator of cellular energy homeostasis. AMPK exists as a heterotrimeric complex composed of a catalytic α subunit and regulatory beta; and gamma; subunits. Binding of AMP to the γ subunit allosterically activates the complex. AMPK is activated in response to stresses that deplete cellular ATP (low glucose, hypoxia and ischemia) and via signaling pathways in response to adiponectin, leptin and CAMKK beta. Recombinant full-length human AMPK (combination of A2/B2/G1 subunits) was expressed by baculovirus in Sf9 insect cells using C-terminal His tags.

• Validated in LanthaScreen™ Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen™ Eu Kinase Binding Assay
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Molecular Weight
63.1/ 31.4/ 38.7 kDa
Quantity
10 µg
Gene Alias
Subunit A2: PRKAA2, AMPK, AMPK2, PRKAA Subunit B2: PRKAB2, MGC61468 Subunit G1: PRKAG1, AMPKG, MGC8666
Host Species
Insect
Recombinant
Yes
Protein Tag
His Tag
Assay Entry
Biochemical binding/kinetic
Kinase Group
Serine/Threonine Kinase
Target Entry
AMPK (A2/B2/G1)
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Full Length
Form
Liquid
Protein Subtype
Serine/Threonine Kinases
Validated Application
Kinase Assay
Species
Human
Research Category
Drug Discovery: Signal Transduction

Contents & Storage

Storage Buffer: 50 mM sodium phosphate pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, 25% glycerol

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.