NUAK2 Recombinant Human Protein

Catalog number: PV6376

NUAK2 Recombinant Human Protein

Catalog number: PV6376
Catalog Number
PV6376
Unit Size
10 µg
Price (USD)
449.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
100 µg
Price (USD)
1,542.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
1 mg
Price (USD)
6,920.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV637610 µg
449.00
Your Price:
***
PV6377100 µg
1,542.00
Your Price:
***
PV63781 mg
6,920.00
Your Price:
***
Product Overview
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NUAK2 or SNF1/AMP kinase-related kinase (SNARK) is a member of the NUAK family of SNF1-like kinase 2. NUAK2 is activated by muscle contraction and is a unique mediator of contraction-stimulated glucose transport in skeletal muscle (1). NUAK2 is involved in cellular stress responses linked to obesity and type 2 diabetes. NUAK2 shows kinase activity against a synthetic test peptide and the activity in keratinocytes is increased by AMP and 5-amino-4-imidazolecarboxamide riboside, implying that AMPK kinase-dependent pathway can activate NAUK2. Glucose deprivation also increases NAUK2 activity in baby hamster kidney fibroblasts. Recombinant full-length human NUAK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

• Validated in LanthaScreen® Kinase Binding Assay
• Protocols available for simple use and optimized performance
• Multiple pack sizes available for convenient use

Related Product:
LanthaScreen® Eu Kinase Binding Assay
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Assay Entry
Biochemical binding/kinetic
Kinase Group
Serine/Threonine Kinase
Target Entry
NUAK2
Expression System
Baculovirus
Protein Form
Recombinant
Species
Human
Validated Application
Kinase Assay
Molecular Weight
96.3 kDa
Quantity
10μg
Gene Alias
SNARK, FLJ90349, DKFZP434J037, DKFZp686F01113
Recombinant
Yes
Protein Tag
GST Tag

Contents & Storage

Storage Buffer: 50 mM Tris-HCl pH 7.5, 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.

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Citations & References