LYN A Recombinant Human Protein, N-GST tag

Catalog number: PV6448

LYN A Recombinant Human Protein, N-GST tag

Catalog number: PV6448
Catalog Number
PV6448
Unit Size
10 µg
Price (USD)
451.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV644810 µg
451.00
Your Price:
***
Product Overview
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LYN (v-yes-1 Yamaguchi sarcoma viral related oncogene homolog) is a SRC family kinase expressed predominantly in hematopoietic, neural, liver, and adipose tissue. It is a protein-coding gene and is associated with diseases such as alexia and chorea-acanthocytosis. Activation of LYN has been shown to lead to imatinib resistance in CML patients. LYN B and the slightly shorter LYN A are the two isoforms of LYN. An important paralog of this gene is FRK. The full length LYN A protein enables researchers to study important mechanisms underlying disease.

• Increase disease relevance by interrogating a purified and active full-length LYN A reagent
• Uncover novel compounds or hits specific to the full length form
• Advance your research using the full-length protein and validated assays

Assay Platforms:
LanthaScreen® TR-FRET Kinase Activity Assay
LanthaScreen® Eu Kinase Binding Assay
Z’-LYTE™ Kinase Activity Assay
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NP_002341.1
Expression System
Insect
Form
Liquid
Protein Form
Full Length
Research Category
Drug Development
Species
Human
Validated Application
Kinase Assay
Molecular Weight
81 kDa
Quantity
10μg
Gene Alias
JTK8, FLJ26625
KinaseFamily
SRC Kinase Family
Recombinant
Yes
Protein Tag
GST Tag

Contents & Storage

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. If properly stored, this product is guaranteed for 6 months from date of purchase.

Suspended in: 50 nM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.

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