LYN A Recombinant Human Protein, N-GST tag

Catalog number: PV6448

LYN A Recombinant Human Protein, N-GST tag

Catalog number: PV6448
Catalog Number
PV6448
Unit Size
10 µg
Price (USD)
Price: 500.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
PV644810 µg
Price: 500.00
Your Price:
***
Product Overview
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Additional Information
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LYN (v-yes-1 Yamaguchi sarcoma viral related oncogene homolog) is a SRC family kinase expressed predominantly in hematopoietic, neural, liver, and adipose tissue. It is a protein-coding gene and is associated with diseases such as alexia and chorea-acanthocytosis. Activation of LYN has been shown to lead to imatinib resistance in CML patients. LYN B and the slightly shorter LYN A are the two isoforms of LYN. An important paralog of this gene is FRK. The full length LYN A protein enables researchers to study important mechanisms underlying disease.

• Increase disease relevance by interrogating a purified and active full-length LYN A reagent
• Uncover novel compounds or hits specific to the full length form
• Advance your research using the full-length protein and validated assays

Assay Platforms:
LanthaScreen™ TR-FRET Kinase Activity Assay
LanthaScreen™ Eu Kinase Binding Assay
Z’-LYTE™ Kinase Activity Assay
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Accession Number
NP_002341.1
Molecular Weight
81 kDa
Quantity
10μg
Gene Alias
JTK8, FLJ26625
KinaseFamily
SRC Kinase Family
Recombinant
Yes
Protein Tag
GST Tag
Expression System
Baculovirus
Protein Family
Kinases & Inhibitors
Protein Form
Recombinant, Full Length
Form
Liquid
Validated Application
Kinase Assay
Species
Human
Research Category
Signal Transduction

Contents & Storage

Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. If properly stored, this product is guaranteed for 6 months from date of purchase.

Suspended in: 50 nM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.