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Invitrogen
Myc Tag Monoclonal Antibody
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FIGURE: 1 / 90
Myc Tag Antibody (R950-25) in WB, ICC/IF
PloS one 2017 -
Fig 3 Elevated mitochondrial ARL2 and ELMOD2 is reversed in mfn1 -/- mfn2 -/- MEFs with restoration of fusion by MFN2. ( A ) mfn1 -/- mfn2 -/- MEFs were transfected with empty vector, or the same vector directing expression of MFN1-myc, MFN2-myc, or MFN2[K109A]-myc. MEFs were fixed 48 hours later and stained for ARL2 (top) and either HSP60 (empty vector) or myc (MFN1-myc, MFN2-myc, MFN2[K109A]-myc) (middle)... View More
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.jpg?time=20240507?time=20240507 "Myc Tag Antibody (R950-25) in WB")
Product Details
R950-25
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Tag
Published species
Tag
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Immunogen
c-Myc synthetic peptide: Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu-
Conjugate
Form
Liquid
Concentration
~1 mg/mL
Purification
purified
Storage buffer
PBS
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
Product Specific Information
NOTE: R950-25 was previously sold under product #46-0603. When re-ordering, please use #R950-25.
This antibody recognizes amino acid sequence: Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu-.
This product contains enough material for 25 Western blots. Western blot against 500 ng of recombinant protein gave a strong signal using chemiluminescent or alkaline phosphatase detection reagents. For Western blot, dilute in PBS containing 0.05% Tween-20 and 5% nonfat, dry milk (PBSTM).
Target Information
Myc is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 46-0603; c Myc; c-myc epitope tag; cmyc; Myc protein; Myc Tag; R950-25; R95025
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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