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Highest antigen sequence indentity to the following orthologs: Mouse (78%), Rat (78%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-110918. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
F-box-like protein which is required for entry into mitosis. Acts by participating in E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDCA 3; Cell division cycle-associated protein 3; gene rich cluster, C8; Gene-rich cluster protein C8; GRCC 8; MGC2577; TOME 1; TOME-1; trigger of mitotic entry 1; Trigger of mitotic entry protein 1
Gene Aliases: C8; CDCA3; GRCC8; TOME-1; TOME1
UniProt ID: (Human) Q99618
Entrez Gene ID: (Human) 83461
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