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Invitrogen
Human SMAGP (aa 60-97) Control Fragment Recombinant Protein
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Product Details
RP-97826
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
YKNKGSYVTYEPTEGEPSAIVQMESDLAKGSEKEEYFI
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (87%), Rat (87%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58895. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Small cell adhesion glycoprotein (SMAGP) is a gene located on chromosome 1p33 that encodes a transmembrane protein involved in cell adhesion processes. SMAGP is primarily expressed in epithelial tissues and plays a role in maintaining cellular architecture and tissue integrity. This glycoprotein contributes to the organization of cell-cell junctions, which are critical for epithelial barrier function and communication between cells. Altered expression of SMAGP has been observed in various cancers, including gastric and colorectal cancers, where it may influence tumor progression and metastasis by affecting cellular adhesion and epithelial-to-mesenchymal transition (EMT). Research into SMAGP continues to explore its functional mechanisms in epithelial biology and its potential as a biomarker for cancer diagnosis and prognosis. By providing insights into the molecular pathways governing cell adhesion and tumorigenesis, studies on SMAGP contribute to the broader understanding of cancer biology and therapeutic opportunities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Small cell adhesion glycoprotein; small cell transmembrane and glycosylated protein; small trans-membrane and glycosylated protein; Small transmembrane and glycosylated protein
Gene Aliases: hSMAGP; SMAGP
UniProt ID: (Human) Q0VAQ4
Entrez Gene ID: (Human) 57228
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