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Invitrogen
Tenascin C (Tenatumomab Biosimilar) Recombinant Human Monoclonal Antibody
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Product Details
MA5-59807
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG1
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
25mM histidine, pH 6.2, with 8% sucrose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Product Specific Information
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
Target Information
Tenascin is a high molecular weight, multifunctional, extracellular matrix glycoprotein expressed in association with mesenchymal-epithelial interactions during development and in the neovasculature and stroma of undifferentiated tumors (Erickson and Bourdon 1989). It has been described under a variety of names: cytotactin, hexabrachion protein, J1, myotendinous antigen (MI) and glioma mesenchymal extracellular matrix (GMEM). The tenascin molecule is a disulfide-linked hexamer. The expression of tenascin is associated with development and growth, both normal and pathological, whereas the distribution in normal adult tissue is restricted.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytotactin; deafness, autosomal dominant 56; ECM glycoprotein; TNC-14/AD1/16; Glioma-associated-extracellular matrix antigen; GMEM; GP 150-225; Hexabrachion; hexabrachion (tenascin); JI; MGC144208; MGC144209; MGC167029; Myotendinous antigen; Neuronectin; Tenascin; Tenascin-C; tenascin-C additional domain 1; tenascin-C FN type III repeat domain; tenascin-C AD1; TN; TN-C; unnamed protein product
Gene Aliases: 150-225; DFNA56; GMEM; GP; HXB; JI; TN; TN-C; TNC
UniProt ID: (Human) P24821
Entrez Gene ID: (Human) 3371
regulation of cell growth
osteoblast differentiation
morphogenesis of an epithelium
cell adhesion
negative regulation of cell adhesion
neuromuscular junction development
positive regulation of cell proliferation
response to wounding
response to mechanical stimulus
positive regulation of gene expression
peripheral nervous system axon regeneration
regulation of cell adhesion
regulation of cell migration
neuron projection development
odontogenesis of dentin-containing tooth
response to ethanol
regulation of inflammatory response
bud outgrowth involved in lung branching
mesenchymal-epithelial cell signaling involved in prostate gland development
prostate gland epithelium morphogenesis
cellular response to retinoic acid
cellular response to vitamin D
response to fibroblast growth factor
cellular response to prostaglandin D stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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