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          • Primary Antibodies ›
          • PPP4C Antibodies

          Invitrogen

          PPP4C Polyclonal Antibody

          View all (29) PPP4C antibodies

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          Cite PPP4C Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (5)
          PPP4C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          PPP4C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 5

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          PPP4C Antibody (PA5-19132) in IHC (P)

          Immunohistochemistry analysis of PPP4C in human small intestine. Samples were incubated with PPP4C polyclonal antibody (Product # PA5-19132) using a dilution of 2.5 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PPP4C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PPP4C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PPP4C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PPP4C Antibody in Western Blot (WB)
          PPP4C Antibody in Western Blot (WB)
          PPP4C Polyclonal Antibody

          Product Details

          PA5-19132

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.1-0.3 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          2-4 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Rat

          Host/Isotype

          Goat / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide sequence (PQETRGIPSKKP) corresponding to the C-terminus amino acids of PPP4C (aa 290-301).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Amount

          100 µg

          Purification

          Ammonium sulfate precipitation

          Storage buffer

          TBS, pH 7.3, with 0.5% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_10981432

          Product Specific Information

          This antibody is predicted to react with canine, rabbit and rat based on sequence homology.

          This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

          Target Information

          The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: epididymis secretory sperm binding protein; P PPX; PP-X; pp4; PP4C; protein phosphatase 4 (formerly X), catalytic subunit; Protein phosphatase X; protein phosphatase X, catalytic subunit; Serine/threonine-protein phosphatase 4 catalytic subunit

          View more View less

          Gene Aliases: PP-X; PP4; PP4C; PPH3; PPP4; PPP4C; PPX

          View more View less

          UniProt ID: (Human) P60510, (Rat) Q5BJ92

          View more View less

          Entrez Gene ID: (Human) 5531, (Rat) 171366

          View more View less

          Function(s)
          phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein binding hydrolase activity metal ion binding lamin binding phosphatase activity protein complex binding protein phosphatase
          Process(es)
          double-strand break repair via homologous recombination regulation of double-strand break repair via homologous recombination regulation of double-strand break repair dephosphorylation cellular response to interleukin-1
          It has to be done as per old AB suggested Products section.

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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