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          • Home
          • › Search Tool
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          • › Hs00609060_m1
          See other BRCA2 GE Assays ›
          Gene Symbol:
          BRCA2
          Gene Name:
          BRCA2, DNA repair associated
          Gene Aliases:
          BRCC2, BROVCA2, FACD, FAD, FAD1, FANCD, FANCD1, GLM3, PNCA2, XRCC11
          Chromosome Location:
          Chr.13: 32315480 - 32399672 on Build GRCh38
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          Assay ID Hs00609060_m1
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information
          • Citations (1)

          Genomic Map

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          Assay Details

          Gene Symbol: BRCA2
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_000059.3 NP_000050.2 13 - 14 7236 126
          GenBank mRNA DQ897648.1 - 12 - 13 7009 126
          U43746.1 - 13 - 14 7237 126

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          More Information


          Updated Mapping Information

          This assay targets the same location as Clariom D transcript cluster(s) TC1300006802.hg.1
          This assay targets the same location as HTA transcript cluster(s) TC13000111.hg.1

          Set Membership:

          Ambion siRNA available Amplicon length greater than or equal to 101 Homo sapiens Human Androgen Panel Inventoried MicroArray Quality Control (MAQC) Human_Androgen Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene BRCA2

          Panther Classification:

          Molecular Function -

          damaged DNA-binding protein

          Gene Ontology Categories:

          Function(s) Process(es)

          telomere maintenance via recombination
          double-strand break repair via homologous recombination
          DNA synthesis involved in DNA repair
          strand displacement
          cytokinesis
          oocyte maturation
          inner cell mass cell proliferation
          nucleotide-excision repair
          double-strand break repair
          DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
          male meiosis I
          spermatogenesis
          brain development
          cell aging
          response to nutrient
          female gonad development
          response to X-ray
          response to UV-C
          response to gamma radiation
          hemopoiesis
          mammary gland development
          chromosome breakage
          homologous chromosome orientation involved in meiotic metaphase I plate congression
          response to estradiol
          regulation of cytokinesis
          negative regulation of mammary gland epithelial cell proliferation
          multicellular organism growth
          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          histone H3 acetylation
          histone H4 acetylation
          positive regulation of transcription, DNA-templated
          positive regulation of mitotic cell cycle
          replication fork protection
          centrosome duplication
          establishment of protein localization to telomere
          mitotic recombination-dependent replication fork processing
          protease binding
          single-stranded DNA binding
          histone acetyltransferase activity
          protein binding
          H3 histone acetyltransferase activity
          H4 histone acetyltransferase activity
          gamma-tubulin binding

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Human Transcriptome Array 2.0 PSR13001173.hg.1 ENST00000544455.1 Ensembl
          Affymetrix Human Transcriptome Array 2.0 PSR13001173.hg.1 NM_000059.3 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR13001173.hg.1 ENST00000380152.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 PSR13001173.hg.1 TC13000111.hg.1 HTA TC
          Affymetrix Human Clariom D Assay PSR1300146304.hg.1 ENST00000380152.7 Ensembl
          Affymetrix Human Clariom D Assay PSR1300146304.hg.1 ENST00000544455.5 Ensembl
          Affymetrix Human Clariom D Assay PSR1300146304.hg.1 ENST00000614259.1 Ensembl
          Affymetrix Human Clariom D Assay PSR1300146304.hg.1 NM_000059.3 Refseq
          Affymetrix Human Clariom D Assay PSR1300146304.hg.1 ENST00000380152.7 Ensembl
          Affymetrix Human Clariom D Assay PSR1300146304.hg.1 ENST00000544455.5 Ensembl
          Affymetrix Human Clariom D Assay PSR1300146304.hg.1 ENST00000614259.1 Ensembl
          Affymetrix Human Clariom D Assay PSR1300146304.hg.1 NM_000059.3 Refseq
          Affymetrix Human Clariom D Assay PSR1300146304.hg.1 TC1300006802.hg.1 Clariom D TC

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          Citations (1)

          Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities.
          Authors
          Press JZ, De Luca A, Boyd N, Young S, Troussard A, Ridge Y, Kaurah P, Kalloger SE, Blood KA, Smith M, Spellman PT, Wang Y, Miller DM, Horsman D, Faham M, Gilks CB, Gray J, Huntsman DG
          Journal
          Bmc Cancer - Page No 17 (Tue Jan 01 00:00:00 EST 2008)
          Volume (Year)
          8 (2008)
          Product Usage
          -

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