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Gibco
Mouse CCL11 (Eotaxin) Recombinant Protein, PeproTech®
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Product Details
250-01-100UG
Applications
Tested Dilution
Publications
Product Specifications
Species
Mouse
Published species
Human,
Mouse
Expression System
E. coli
Amino acid sequence
HPGSIPTSCC FIMTSKKIPN TLLKSYKRIT NNRCTLKAIV FKTRLGKEIC ADPKKKWVQD ATKHLDQKLQ TPKP
Molecular weight
8.4 kDa
Class
Recombinant
Type
Protein
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
Murine Eotaxin was found to induce chemotaxis of purified eosinophils at concentrations ranging between 10-100 ng/ml.
Conjugate
Form
Lyophilized
Amount
100 µg
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
Recombinant Murine Eotaxin is an 8.4 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C-C motif chemokine 11; Eosinophil Chemotactic Factor; Eosinophil chemotactic protein; Eotaxin; Eotaxin 1; Eotaxin1; MGC22554; small chemokine (C-C motif) ligand 11; small inducible cytokine A11; Small-inducible cytokine A11
Gene Aliases: Ccl11; eotaxin; Scya11
UniProt ID: (Mouse) P48298
Entrez Gene ID: (Mouse) 20292
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