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Invitrogen
Human ADAMTS1 Recombinant Protein
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Product Details
RP-77543
Product Specifications
Expression System
Insect cells
Class
Recombinant
Type
Protein
Conjugate
Form
Liquid
Amount
5 µg
Storage conditions
-80°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
RP-77543 is a purified, truncated recombinant human ADAMTS1 protein expressed in insect cells.
RP-77543 may be used as a control with corresponding anti-ADAMTS1 antibodies. ADAMTS1 is inhibited by chelators of divalent cations such as EDTA and catechin gallate esters.
Target Information
ADAMTS-1 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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