Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This peptide corresponds to 15 amino acids near the center of human Acinus.
PEP-0065 can be used as a blocking peptide with polyclonal antibody PA5-19940.
ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.
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Protein Aliases: Acinus; Apoptotic chromatin condensation inducer in the nucleus; DKFZp667N107; functional spliceosome-associated protein 152
Gene Aliases: ACIN1; ACINUS; ACN; fSAP152; KIAA0670
UniProt ID: (Human) Q9UKV3
Entrez Gene ID: (Human) 22985
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