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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84771. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
cDNA encoding BCAS2 has been isolated. The deduced 225-amino acid protein contains a central potential N-glycosylation site and multiple N-terminal potential phosphorylation sites. Northern and Southern blot analyses demonstrates expression of a 1.5-kb transcript at various levels in multiple breast cancer cell lines, with greatest amplification in BT-20 and MCF-7 cells. BCAS2 is ubiquitously expressed in normal tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Breast carcinoma-amplified sequence 2; DNA amplified in mammary carcinoma 1 protein; Pre-mRNA-splicing factor SPF27; spliceosome associated protein, amplified in breast cancer; Spliceosome-associated protein SPF 27
Gene Aliases: BCAS2; DAM1; Snt309; SPF27
UniProt ID: (Human) O75934
Entrez Gene ID: (Human) 10286
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