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Invitrogen
Human C11orf80 Control Fragment Recombinant Protein
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Product Details
RP-97481
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
SYSQDMTGVTPFQMIFEVDEKPRTLMTDCLVIKHFLRKIIMVHPKVRFHFSVKVNGILSTEIFGVENEPTLNLGNGIALLVDSQHYVSRPNFGTIESHC
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (62%), Rat (62%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58597. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
TOP6BL (topoisomerase VI-like protein B) encodes a protein related to the B subunit of archaeal topoisomerase VI, suggesting a role in DNA topology and genome maintenance. It is expressed in human tissues and has been implicated in processes like chromatin organization and meiosis, though its exact molecular functions and clinical relevance are still being clarified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: TOP6B like initiator of meiotic double strand breaks; TOPOVIBL; Type 2 DNA topoisomerase 6 subunit B-like; Type 2 DNA topoisomerase VI subunit B-like; unnamed protein product
Gene Aliases: C11orf80; HYDM4; TOP6BL; TOPOVIBL
UniProt ID: (Human) Q8N6T0
Entrez Gene ID: (Human) 79703
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