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Invitrogen
Human CLK1 (aa 76-135) Control Fragment Recombinant Protein
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Product Details
RP-105230
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
YRNDYTQGCEPGHRQRDHESRYQNHSSKSSGRSGRSSYKSKHRIHHSTSHRRSHGKSHRR
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (73%), Rat (73%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66487. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
CLK1 is a dual specificity kinase that phosphorylates PTP-1B and members of the SR family of splicing factors. It is thought to be involved in neuronal differentiation and mRNA splicing. Therefore, the encoded protein may play an indirect role in governing splice site selection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDC-like kinase 1; CDC28/CDC2-like kinase; Dual specificity protein kinase CLK1; Protein kinase CLK1; protein tyrosine kinase STY
Gene Aliases: CLK; CLK/STY; CLK1; STY
UniProt ID: (Human) P49759
Entrez Gene ID: (Human) 1195
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