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Invitrogen
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This product is a GST-tagged recombinant protein corresponding to full-length human D4-GDI.
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 54kDa.
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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