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Invitrogen
Human DISP2 (aa 209-317) Control Fragment Recombinant Protein
Product Details
RP-98095
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
DIGSKLVVWRALQALTGPRKLLFLSPDLELNSSSSHNTLRPAPRGSAQESAVRPRRMVEPLEDRRQENFFCGPPEKSYAKLVFMSTSSGSLWNLHAIHSMCRMEQDQIR
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (68%), Rat (68%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63790. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
DISP2, also known as dispatched homolog 2, is a protein that plays a critical role in the regulation of the hedgehog signaling pathway. It is involved in the transport and release of hedgehog ligands, which are important for cellular differentiation and tissue development. Mutations in the DISP2 gene have been associated with various developmental disorders, including holoprosencephaly and cleft lip and palate. DISP2 is also being studied as a potential therapeutic target in cancer, as the hedgehog pathway is frequently dysregulated in various types of tumors
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dispatched B; dispatched homolog 2; Protein dispatched homolog 2
Gene Aliases: C15orf36; DISP2; DISPB; HsT16908; KIAA1742; LINC00594
UniProt ID: (Human) A7MBM2
Entrez Gene ID: (Human) 85455
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