Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (71%), Rat (71%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4. 1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 4.1R; Band 4.1; elliptocytosis 1, RH-linked; EPB4.1; Erythrocyte membrane protein band 4.1; erythrocyte surface protein band 4.1; P4.1; Protein 4.1
Gene Aliases: 4.1R; E41P; EL1; EPB41; HE
UniProt ID: (Human) P11171
Entrez Gene ID: (Human) 2035
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