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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (75%), Rat (75%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54440. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 80 kDa MCM3-associated protein; FLJ44336; FLJ45306; GANP; germinal center-associated nuclear protein; Germinal-center associated nuclear protein; germinal-centre associated nuclear protein; MCM3 acetylating protein; MCM3 acetyltransferase; MCM3 import protein; MCM3 minichromosome maintenance deficient 3 associated protein; MCM3AP
Gene Aliases: GANP; KIAA0572; MAP80; MCM3AP; SAC3
UniProt ID: (Human) O60318
Entrez Gene ID: (Human) 8888
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