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          • Proteins & Peptides ›
          • HINT1 Proteins

          Invitrogen

          Human HINT1 Synthetic Peptide

          View all (2) HINT1 proteins

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          Cite Human HINT1 Synthetic Peptide

          Product Details

          PEP-0733

          Applications
          Tested Dilution
          Publications

          Neutralization (Neu)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human

          Class

          Synthetic

          Type

          Peptide

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          200 µg/mL

          Purification

          purified

          Storage buffer

          PBS, pH 7.2, with 0.1% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Product Specific Information

          This peptide corresponds to 17 amino acids near the center of human HINT1.

          PEP-0733 can be used as a blocking peptide with polyclonal antibody PA5-20613.

          Target Information

          Histidine triad nucleotide-binding protein 1 (HINT1) is a member of the histidine triad (HIT) protein family, a group of small nucleotide-binding and -hydrolyzing proteins. HINT1 interacts with several diverse proteins and has been suggested to have tumor suppressive activities. HINT1 catalyzes the hydrolysis of adenosine 5'-monophoramidate substrates such as AMP-morpholidate, but its enzymatic function does not appear to play a role in its tumor suppression. Recent experiments demonstrate that HINT1 forms a complex with POSH and JNK in vivo, inhibiting AP-1 activity and the phosphorylation of c-Jun, and this action could contribute to the tumor suppressor activity of HINT1. Other studies raise the possibility of HINT1 as a candidate gene for schizophrenia.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: adenosine 5'-monophosphoramidase; Adenosine 5'-monophosphoramidase HINT1; Desumoylating isopeptidase HINT1; FLJ30414; FLJ32340; Histidine triad nucleotide-binding protein 1; PKCI-1; Protein kinase C inhibitor 1; Protein kinase C-interacting protein 1

          View more View less

          Gene Aliases: HINT; HINT1; NMAN; PKCI-1; PKCI1; PRKCNH1

          View more View less

          UniProt ID: (Human) P49773

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          Entrez Gene ID: (Human) 3094

          View more View less

          It has to be done as per old AB suggested Products section.
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