Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51938. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Hepatocyte nuclear factor 6 is a CUT homeobox family protein which is a transcription factor and contains a CUT DNA-binding domain and a homeobox DNA-binding domain. It is an upstream regulator of several genes involved in the pathogenesis of maturity-onset diabetes of the young. HNF6 is a ligand of the FOXM1 transcription factor network. HNF6, along with HNF4, controls gene expression in the liver. The expression levels of HNF6 and HNF4 rise steadily during development and that up- or down regulation of HNF6 and HNF4 expression generate premature or delayed expression of the g6pc gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Hepatocyte nuclear factor 6; hepatocyte nuclear factor 6, alpha; HNF-6; One cut domain family member 1; One cut homeobox 1
Gene Aliases: HNF-6; HNF6; HNF6A; ONECUT1
UniProt ID: (Human) Q9UBC0
Entrez Gene ID: (Human) 3175
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