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Invitrogen
Human IFN-omega Recombinant Protein
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Product Details
BMS304
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Molecular weight
20 kDa
Class
Recombinant
Type
Protein
Purity
>95% prior to addition of human serum albumin
Conjugate
Form
Liquid
Concentration
50 µg/mL
Purification
purified
Storage buffer
PBS with 20mg/mL BSA
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Description: In the human genome, the IFN-omega gene family consists of seven members located on chromosome 9. However, only one of these genes is functional giving rise to the IFN-omega protein, whereas the others are non-functional pseudogenes. The IFN-omega gene is not expressed in unstimulated cells. Viral infection results in expression of the gene giving rise to the N-glycosylated protein consisting of 172 or 174 amino acids and an apparent molecular mass of about 25kDa. A single carbohydrate group consists mainly of biantennary complex oligosaccharides with variable amounts of N-acetyl neuraminic acid. In quantitative terms, IFN-omega is a major component of human leukocyte IFN; with a contribution to its total antiviral activity estimated to be in the range of 10 -15 %.
Purity: >95% prior to addition of human serum albumin.
Molecular Weight: 20.0 kDa.
Target Information
IFN-omega is a type I interferon that can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-alpha, IFN-beta, and IFN-omega, signal through the IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities. IFN-omega exhibits about 75% sequence homology with IFN-alpha, and contains two conserved disulfide bonds that are necessary for full biological activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: IFN o; IFN ω; IFN-omega 1, interferon omega-1; IFNo; IFNomega; IFNW; IFNω; Interferon; Interferon alpha-II-1; Interferon o; Interferon OMEGA; Interferon omega-1; Interferon ω; interferon, omega 1
Gene Aliases: IFNW1
UniProt ID: (Human) P05000
Entrez Gene ID: (Human) 3467
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