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Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62314. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a voltage-gated potassium channel alpha subunit predominantly expressed in the forebrain. Studies in mice have found that cognitive function increases when this gene is knocked out. In humans, the encoded protein has been shown to be capable of binding glycoprotein 120 of the human immunodeficiency virus type 1 (HIV-1) envelope. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BEC1; Brain-specific eag-like channel 1; ELK channel 2; ether-a-go-go K(+) channel family member; Ether-a-go-go-like potassium channel 2; potassium channel, voltage gated eag related subfamily H, member 3; Potassium voltage-gated channel subfamily H member 3; potassium voltage-gated channel, subfamily H (eag-related), member 3; Voltage-gated inwardly rectifying potassium channel KCNH3; Voltage-gated potassium channel subunit Kv12.2
Gene Aliases: BEC1; ELK2; KCNH3; KIAA1282; Kv12.2
UniProt ID: (Human) Q9ULD8
Entrez Gene ID: (Human) 23416
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