Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (31%), Rat (31%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62939. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this intronless gene is a member of a large family of histone lysine demethylases, which use oxygen and 2-oxoglutarate to demethylate di- and trimethylated lys9 of histone H3. Derepression of genes by demethylases is sometimes involved in viral infection or carcinogenesis, so inhibitors of these enzymes are desired.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: [histone H3]-trimethyl-L-lysine(9) demethylase 4E; KDM4D-like protein; lysine (K)-specific demethylase 4E; Lysine-specific demethylase 4D-like; Lysine-specific demethylase 4E
Gene Aliases: JMJD2E; KDM4DL; KDM4E
UniProt ID: (Human) B2RXH2
Entrez Gene ID: (Human) 390245
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