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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-140208. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: importin alpha 4; Importin alpha Q2; importin alpha-3; importin subunit alpha-3; Importin subunit alpha-4; importin-alpha-Q2; karyopherin alpha 3 (importin alpha 4); Karyopherin subunit alpha-3; Qip2; RP11-432M24.3; SRP1-gamma
Gene Aliases: hSRP1; IPOA4; KPNA3; QIP2; SRP1; SRP1gamma; SRP4
UniProt ID: (Human) O00505
Entrez Gene ID: (Human) 3839
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