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Highest antigen sequence indentity to the following orthologs: Mouse (77%), Rat (77%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53339. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in this gene are associated with dyslexia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dyslexia susceptibility 2; Dyslexia-associated protein KIAA0319; mKIAA0319; neuronal migration
Gene Aliases: DYLX2; DYX2; KIAA0319; NMIG
UniProt ID: (Human) Q5VV43
Entrez Gene ID: (Human) 9856
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