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Invitrogen
Human LGI1 Synthetic Peptide
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Product Details
PEP-0626
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
This peptide corresponds to 13 amino acids near the amino terminus of human LGI1.
PEP-0626 can be used as a blocking peptide with polyclonal antibody PA5-20506.
Target Information
The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Epitempin 1; Epitempin-1; leucine-rich glioma inactivated 1; Leucine-rich glioma-inactivated protein 1; leucine-rich, glioma inactivated 1; OTTHUMP00000020121; OTTHUMP00000020122
Gene Aliases: ADLTE; ADPAEF; ADPEAF; EPITEMPIN; EPT; ETL1; IB1099; LGI1; UNQ775/PRO1569
UniProt ID: (Human) B4E1S0
Entrez Gene ID: (Human) 9211
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