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Invitrogen
Human MAEL Synthetic Peptide
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Product Details
PEP-1037
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Amount
50 µg
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human Maelstrom.
PEP-1037 can be used as a blocking peptide with polyclonal antibody PA5-20923.
Target Information
The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cancer/testis antigen 128; maelstrom homolog; Protein maelstrom homolog; RP11-102C16.1; spermatogenesis associated 35; testicular tissue protein Li 116; unnamed protein product
Gene Aliases: CT128; MAEL; SPATA35
UniProt ID: (Human) Q96JY0
Entrez Gene ID: (Human) 84944
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