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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53559. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Mediator complex subunit 21; Mediator of RNA polymerase II transcription subunit 21; RNA polymerase II holoenzyme component SRB7; RNAPII complex component SRB7; SRB7 suppressor of RNA polymerase B homolog
Gene Aliases: hSrb7; MED21; SRB7; SURB7
UniProt ID: (Human) Q13503
Entrez Gene ID: (Human) 9412
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