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This peptide corresponds to 17 amino acids near the carboxy terminus of human MED4.
PEP-0691 can be used as a blocking peptide with polyclonal antibody PA5-20571.
The Mediator is a multiprotein coactivator that is required by DNA-binding transcription factors for activation of polymerase II transcribed genes. MED4 appears to be a core Mediator subunit and is found in nearly all Mediator preparations (Sato et al., 2004).
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Protein Aliases: Activator-recruited cofactor 36 kDa component; ARC36; DRIP36; FLJ10956; Mediator complex subunit 4; Mediator of RNA polymerase II transcription subunit 4; mediator, 34-kD subunit, homolog; RP11-90M2.2; TRAP/SMCC/PC2 subunit p36; TRAP/SMCC/PC2 subunit p36 subunit; vitamin D receptor-interacting protein, 36-kD; Vitamin D3 receptor-interacting protein complex 36 kDa component
Gene Aliases: ARC36; DRIP36; HSPC126; MED4; TRAP36; VDRIP
UniProt ID: (Human) Q9NPJ6
Entrez Gene ID: (Human) 29079
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