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Invitrogen
Human MINA53 Synthetic Peptide
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Product Details
PEP-1023
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Amount
50 µg
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
This peptide corresponds to 15 amino acids near the amino terminus of human MINA.
PEP-1023 can be used as a blocking peptide with polyclonal antibody PA5-20909.
Target Information
MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 60S ribosomal protein L27a histidine hydroxylase; Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA; DKFZp762O1912; FLJ14393; Histone lysine demethylase MINA; MDIG2; cell cycle regulatory protein; mineral dust induced gene; mineral dust induced gene protein; mineral dust-induced gene; Mineral dust-induced gene protein; mineral dust-induced protein; mina53; nucleolar protein; NO52; ribosomal oxygenase 2; RIOX2; JMJD10; MYC induced nuclear antigen; MYC-induced nuclear antigen; MYC-induced nuclear antigen 53; myc-induced nuclear antigen, 53 kDa; Nucleolar protein 52; Protein mina53; Ribosomal oxygenase 2; Ribosomal oxygenase MINA; ROX; unnamed protein product
Gene Aliases: JMJD10; MDIG; MINA; MINA53; NO52; RIOX2; ROX
UniProt ID: (Human) Q8IUF8
Entrez Gene ID: (Human) 84864
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